The selected egg donors are healthy women between 18 and 29 years of age who donate eggs voluntarily, anonymously and altruistically.
The donor selection process is very rigorous. As a general rule, one out of every three candidates is accepted.
The selection protocol consists of the following steps:
In-depth psychometric interview and evaluation to rule out inappropriate habits or psychiatric or psychological disorders.
Detailed personal and family medical history to rule out heredofamilial diseases.
- Evaluation of phenotypic characteristics, personal and social habits.
- Provision of informed consent for egg donation .
- Photographic record for Procreareggbank’s internal and confidential medical use.
- Physical, genital and mammary examination with cervicovaginal cytology.
- Transvaginal Ultrasound
Antral follicle count and antimullerian hormone assessment if applicable.
- Group and Rh
- Complete blood count
- Coagulation study
Study of sexually transmitted diseases:
- Hepatitis B surface antigen
- Anti-hepatitis B core antibodies
- Anti-hepatitis C antibodies
- Anti-HIV-1 + HIV-2 antibodies
- Serology Lues R.P.R.
- Karyotype in peripheral blood.
- CarrierMap genetic test: The donor is tested for 515 possible mutations related to more than 300 genetic diseases, discarding donors with the following mutations:
1. Adrenoleukodystrophy: X-Linkeda (ABCD1)
2. Alpha Thalassemia (HBA2,HBA1)
3. Sickle-Cell Anemia (HBB)
4 Spinal Muscular Atrophy: SMN1 Linked (SMN1)
5 Beta Thalassemia (HBB)
6. Choroideremia (CHM)
7. Factor IX Deficiency (F9)
8. Factor VIII Deficiency (F8)
9. Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD)
10. Ornithine Transcarbamylase Deficiency (OTC)
11. Pyruvate Dehydrogenase Deficiency (PDHA1)
12. Hypohidrotic Ectodermal Dysplasia: X-Linked (EDA)
13. DMD-Related Muscular Dystrophies (DMD)
14. Chronic Granulomatous Disease: X-Linked (CYBB)
15. Charcot-Marie-Tooth Disease with Deafness: X-Linked: GJB1 Related (GJB1)
16. Charcot-Marie-Tooth Disease with Deafness: X-Linked: PRPS1 Related (PRPS1)
17. Fabry’s Disease (GLA)
18. Cystic Fibrosis (CFTR)
19. Hemoglobinopathy: Hb O (HBB)
20. Hemoglobinopathy: Hb C (HBB)
21. Hemoglobinopathy: Hb D (HBB)
22. Hemoglobinopathy: Hb E (HBB)
23. Myotubular Myopathy: X-Linked (MTM1)
24. Emery-Dreifuss Myopathy: X-Linked (EMD)
25. Juvenile Retinoschisis: X-Linked (RS1)
26. SCID: X-linked (IL2RG)
27. Lowe Oculocerebrorenal Sydrome (OCRL)
28. Alport Syndrome: X-linked (COL4A5)
29. Arts Syndrome (PRPS1)
30. Hunter Syndrome (IDS)
31. Wiskott-Aldrich Syndrome (WAS)
32. Fragile X Syndrome (FMR1)
33. Androgen Insensitivity Syndrome: Complete (AR)
34. Copper Transport Disorders (ATP7A)
35. Nonsyndromic Hearing Loss and Deafness: GJB2 Related (GJB2)
36. Alpha-1-Antitrypsin Deficiency SERPINA1
37. 21-Hydroxylase-Deficient Classical Congenital Adrenal Hyperplasia (CYP21A2)
38. 21-Hydroxylase-Deficient Nonclassical Congenital Adrenal Hyperplasia (CYP21A2)
Note: it is possible to perform genetic matching with bank or partner semen.
PROTOCOL FOR VITRIFICATION OF OOCYTES
The oocytes are vitrified using the KITAZATO method.
Donor report to the laboratory requesting our services.
The report states:
- Phenotypic data:
- Group and Rh
- Hair color
- Eye color
- Test data (serology and genetic studies)
- Egg vitrification technique.